Antivirus effect on new colonas found in catechin, persimmon astringent, natto, and the latest food research

With the expansion of the new colon virus infections, the antiviral effects of food we usually eat are being verified.In the near future, we will introduce three latest food research, which may have food that can be expected to have new health benefits.

1."High concentration catechin" inactivated effect of new Corona influenza, etc.

A company that develops and researches various materials used in foods and cosmetics, etc., HPG Co., Ltd., has a high concentration of EGCG (EGCG (Epigarocatekin Galate), which is a type of catechin, and has a high concentration in an aqueous solution.He succeeded in raising.

The stable high -concentration catechin EGCG developed by the technology is a new coloner, influenza, and SARS virus, led by Professor Masahiko Kurokawa, Professor Masahiko Kurokawa, Director of Pharmaceutical Science, and Pharmaceutical Science.The effective inactivation effect was demonstrated.

● Demonstrate the inactivated effect of new colona, influenza, and SARS virus

This stable high -concentration catechin EGCG has an inactivated effect on influenza virus, SARS virus, new colonavirus, etc., which repeats mutations through research by the Deputy President of the Kyushu Health and Welfare University, Professor Masahiko Kurokawa, etc.It was revealed that there was.

The mechanism is that the stable high -concentration catechin EGCG is binding to the protein on the virus particles surface to prevent intrusion into biological cells.

● Expectations for commercialization of food from safety

According to HPG CEO Masanori Kanayama, who gave a lecture the other day at the presentation of this demonstration result, the development of the development was "as a countermeasure against viruses, and it will be a matter of whether it will be useful for everyone's life, and this result will finally be obtained.Ta.

The advantage of this high -concentration catechin is that all components that have realized stabilization are food additive components allowed by the Ministry of Health, Labor and Welfare.Even if you enter your body, there is no worry about side reactions, and it is possible to take oral care from children to the elderly with peace of mind.

In addition, depending on the additional concentration, if the concentration shows an inactivation effect, there is almost no damage to the original taste, fragrance and color of existing products due to the bitterness, bitterness, discoloration, etc. specific to catechin EGCG, and in various fields.It can be expanded to the product.

Spray and tablet made as a sample product

Soft drinks and alcoholic beverages made as sample products

We added it to commercially available lemon beverages, cola drinks, carbonated water, domestic shochu, Chinese shochu white sake, and verified virus inactivation, but since the virus was inevitable, these were still present.It can be expected to be versatile to develop a variety of drinks as a beverage with antiviral function.

It is also expected to be used for virus preventive oral care, finger disinfection, food and beverage development, and domestic influenza prevention measures.

2.Tannins in "persimmon astring" succeeded in inactivating the new colon virus

Professor Toshihiro Ito and Professor Toshiichi Yano of Nara Prefectural Medical University, and the MBT Consortium, a general incorporated association in collaboration with the university, announced that the new colonavirus was succeeded by using high -purity persimmon astringent in September 2020. did.

Tannins in persimmons will reduce the infectious new coronavirus to less than 1 / 10,000.

● Co -research between Nara Prefectural Medical University and manufacturers

The results of joint research with UHA flavor sugar, Kabaya Foods, Canlo, and Kasugai Seika, a member of the MBT Consortium, were announced in February to March in 2021.

In a collaborative study with UHA flavor sugar, Kanro, and Kasugai Seika, the new Coronavirus has been confirmed in "Kaki Shibu -containing candy", and in a joint study with Kabaya Foods, the new colon virus is inactivated.

When he interviewed Kanro, he participated in a joint research on foods using persimmon astringent, aiming for future social contributions to the expansion of the new colon virus that has not yet converged.

Kaki Shibu uses high -purity persimmon astringent made by Ishii & Co., Ltd. (Gojo City, Nara Prefecture).It is an odorless persimmon astringent powder obtained for food with a unique manufacturing method, and contains a large amount of reddish brown persimmon tannins.Persimmon astringent has long been a preservative effect, and is indispensable for people's lives, such as being used for paint and dyes.

3."Natto extract" inhibits the infection of the new colonovirus into cultured cells

National University Corporation, Faculty of Agriculture, Agriculture, Infectious Diseases, Future Epidemiology Research Center, Infection of natto extract (new colon virus) with natto extract in a joint research with Miyazaki University and Takano Foods Co., Ltd.It was announced in July 2021 that he had found to inhibit.

In the experiment, Takano Foods Co., Ltd. uses natto extract of "amazing natto S-903".

It proved that the substance contained in the natto extract breaks the infection by breaking down the receptor-binding region of the spike protein on the surface of SARS-COV-2.

● The direct antiviral effect of food is shown

In the past, there have been few cases of food direct antiviral effects, and it is a study that triggers the values of traditional foods in the emergency.

We talked to Professor Tetsuya Mizutani, director of the research center who was involved in this study.

"The effects of food infections have been described in the" enhancement of immunity ". This is (1) the food activates immunity, and (2) the activated immunity prevents virus infection.It is made up of two stages. However, in many cases only (1) is proven, and it is quite difficult to show the effect of (2). Foods are quite effective.If possible, the ultimate way of thinking will not be necessary. It is better to take it than those who do not take food that raises immunity.

So we wondered if we could prove the antiviral effect of food more directly.And I learned that natto bacteria have 80 kinds of protein -degrading enzymes.This is a matter of course, because natto bacteria have to digest boiled beans with all their might.80 types are kitchen knives, scissors, swords and guns.I thought that one of them could disassemble the new colon virus.Then, the protein -degrading enzyme of natto bacteria was inactivated by decomposing the new colon virus spike protein.Research is undergoing research on other viruses. "

● Possibility of future

This study is an experiment using culture cells, not indicating that eating natto can prevent SARS-COV-2 infection.

In that case, I am worried about how to use food development in the future.

"We are going to break down the pathogens such as viruses in food and move in the direction of making safe and secure foods. The final goal is dying with foods contaminated with pathogens.It is to save the children. While aiming for that, the mechanism of the anti -infectious diseases of food will be a basic research, food development will be commercialized and will contribute to the world in both wheels. "

A new colon virus infection that rampages worldwide.Research on inactivation from food will continue to accelerate.I hope that it will be commercialized in the near future.

[Reference] HPG "New Corona, such as Corona, is inactivated by viruses in an aqueous solution of [Green Tea Catechin EGCG] HPG Co., Ltd. HPG Co., Ltd. succeeded in HPG Co., Ltd.Tokyo University of Agriculture and Technology "It turns out that natto extractions inhibit the infection of the new colon virus to the culture cell -Expectations to contribute to the prevention of infection-"

Interview / sentence / Akari Ishihara